Canine Cushing's Syndrome (also known as hyperadrenocorticism) is a condition resulting from the over-production of cortisone by the adrenal glands. The adrenals are two small glands located near the kidneys. They normally produce a small amount of cortisone daily, helping the body to cope with the numerous little stresses that occur in everyday life. Cortisone is necessary in small amounts. Problems arise when an over-production occurs.

There are two forms of Canine Cushing's Syndrome:

85% of the dogs with Cushing's Syndrome have the first form, which is fortunate because this form is much easier to treat. This type of Cushings usually results from a small benign growth in the Pituitary gland. This growth produces a chemical that directs the adrenal glands to continuously produce cortisone, eventually leading to changes in the body that are detrimental.

The second form of Cushing's Syndrome usually results from a malignant growth in one of the adrenal glands. The end result is the same as the pituitary form, the over-production of cortisone, however this form is more difficult to treat due to the malignant nature of the growth.

Too much cortisone leads to a multitude of problems. It suppresses the immune system, leading to infection. It affects muscle, leading to weakness and heart disease. The list is lengthy because the problem affects every system of the body.

At home the owner usually notices any one, or all, of the following signs:

Diagnosis involves several testing procedures and sometimes can be elusive to confirm. Tests are also necessary to differentiate which type of Cushing’s is present. Treatment depends on the type of Cushing's and is lifelong. Without treatment, the pet's life is shortened and subject to many illnesses.